Dairy Ice Cream, No Cow Needed: These Egg And Milk Proteins Are Made Without Animals

Aug 2, 2019
Originally published on August 9, 2019 11:44 am

Earlier today, I ate a scoop of chocolate ice cream – creamy and pleasantly fatty feeling in my mouth. This would hardly seem newsworthy, except for the high-tech ingredient that made my frozen treat go down so smoothly: dairy proteins produced in a lab, no cows needed.

The realm of plant-based meat substitutes has gotten a lot of buzz lately. Think the Impossible Burger and Beyond Meat – companies that use biochemistry to mimic the taste and texture of meat using plant-based ingredients. There's another frontier along these lines – start-ups that use microbes to create egg, dairy and other animal proteins without the animals.

Their pitch: Sustainability. Livestock agriculture uses lots of water and land resources, and produces significant amounts of greenhouse gases.

"If you can produce just the proteins that you want without keeping a living animal alive, that's going to be a lot more efficient, so it's better for the environment," says Bruce Friedrich of the Good Food Institute, which promotes plant- and cell-based alternatives to animal protein. And he says as the technology scales up, it should be a lot cheaper to produce proteins this way, too.

Among the early entrants in this field is Perfect Day, producer of the aforementioned ice cream. The company took the genetic code for the main proteins in whey, a byproduct of cheese-making, then had it artificially synthesized into a molecule of DNA – so the process is "totally animal free," says Perfect Day co-founder Ryan Pandya. Then they genetically engineered microbes to produce the same proteins through fermentation.

"Just like cows eat plants and make milk, it turns out [micro]flora can eat plants and make milk. And that's all we've done," Pandya says.

"The process is really simple," he says. You take a tank of microbes, feed them, and they turn into milk protein. "Then you separated it out with filtration and drying and you're done."

Why focus on whey? In frozen desserts, whey protein provides velvety texture – Perfect Day released its ice cream in a limited run of about 1,000 3-pint boxes as a sort of proof of concept to introduce consumers to its technology. (Bonus: It's also lactose free.)

But the company's goal is actually to become an ingredient supplier to all the food companies that rely on whey to boost protein levels in a range of foods, from smoothies to power bars. The target audience goes beyond vegans — to everyone.

"Rather than try to compete with all these big food makers that are otherwise just going to buy a ton of whey protein from factory-farmed cows, we can actually give them a better supply chain and in so doing, we can have a lot more impact than we would on our own," Pandya says.

Other companies looking to shake up the food supply include Motif Ingredients, which launched earlier this year with $90 million in investor financing. It aims to produce alternatives to dairy, egg and meat proteins using microbial fermentation and supply them to food makers.

Clara Foods is using a similar synthetic biology process to create egg white proteins, including a highly soluble protein that would be used in sports drinks and other beverages. That could hit the food market early next year, says Ranjan Patnaik, vice president for technology strategy and operational excellence. Another protein in the pipeline could be used as egg whites — think vegan meringue and baked goods.

"We have made all kinds those of pound cake, meringue, other recipes" in their development lab in the San Francisco Bay Area, Patnaik says.

New Culture, another California startup, is also targeting dairy: It's using microbial fermentation to make casein, milk proteins that give cheese its stretchy quality – which, alas, many vegan cheeses today seem to lack, says co-founder Inja Radman.

If all this sounds a little too futuristic, consider this: Much of the cheese produced today already relies on the same technology in the form of rennet, an enzyme used to curdle milk. Cheese makers used to get it from the stomachs of slaughtered calves but for many years now, much of the rennet used for cheese has been made via microbial fermentation, notes Friedrich.

Given that this technology is already out there, and that the synthetic animals proteins produced are exact genetic replicas of the real thing, the companies making them don't anticipate major hurdles with regulators at the Food and Drug Administration.

Some critics — like Dana Perls, senior food campaigner for the environmental group Friends of the Earth — are concerned that the FDA will not give sufficient scrutiny to this new wave of synthetic proteins. Perls worries that the adoption of these proteins will make our food supply even more dependent on the fruits of biotechnology. "The real solution for climate chaos and animal welfare problems are the truly organic, plant-based sources of proteins and organic solutions for less and better meat," Perls says.

Many dairy farmers are also not on board. For one thing, says Alan Bjerga of the National Milk Producers Federation, an industry group that represents dairy producers, products made with synthetic dairy proteins may not have the same nutritional profile – such as vitamin and mineral content — as those made with milk from real cows.

"We want to make sure that consumers are very informed that these are not nutritionally the same," he says.

Others in the food industry, however, have embraced the new start-ups. Archer Daniels Midland, a global ingredient and food processing company, has partnered with Perfect Day. Fonterra, a multinational dairy giant based in New Zealand, is an investor in Motif Ingredients. And Clara Foods has teamed up with Ingredion, which supplies ingredients to the food and beverage industry, among others.

Copyright 2020 NPR. To see more, visit https://www.npr.org.


On this hot August day, we are going to dip into some ice cream - not just any ice cream. This ice cream represents a scientific breakthrough. Here's what's up. Lots of researchers are trying to create food from plants that taste like meat. Burger King starts offering its plant-based Impossible Whopper across the country next week. Now we're talking about companies that use microbes to create animal proteins without the animals. To explain more, NPR food editor Maria Godoy is here in the studio.

Hey, Maria.


SHAPIRO: I'd be interested in this story even if it did not give me a chance to eat ice cream, but I am especially interested by what you have in front of you right here.

GODOY: Right. Well, what we have right here is an ice cream from a company called Perfect Day. And what they did is they took milk protein, called whey, and they created a synthetic version of it. And then they trained microbes - they genetically engineered microbes to produce this whey protein in vast quantities. So basically, they turned the microbes into little protein factories, and there was no animal involved in the process, the company says, so it's basically vegan. And then they put the whey in ice cream, and what whey does in ice cream is it gives it a nice creamy, velvety texture.

SHAPIRO: So you've got a pint of milk chocolate and a pint of vanilla salted fudge in front of you.

GODOY: That's right. You want to try it?

SHAPIRO: Of course I want to try it.

GODOY: I came armed with scoops. Let's see. All right, here you go.

SHAPIRO: All right. It's really good ice cream.

GODOY: It tastes like ice cream, right?

SHAPIRO: I would totally put this next to Breyers or Ben and Jerry's.


SHAPIRO: Does this company think the market is mostly vegans or do they think it's bigger than that?

GODOY: So here's the thing. Yeah, they want to make better options for vegans, but, really, what they want to do is change the way all of us eat, especially omnivores. The whole idea is that livestock agriculture uses a huge amount of land and water resources, and it produces significant greenhouse gas emissions. And so what these companies say is, if you can produce the animal proteins you want without having to raise all those cows, you're going to be a lot more sustainable. And ultimately, they say, they can produce those proteins cheaper, too.

SHAPIRO: Could other foods be produced this way?

GODOY: There are other people looking at different animal proteins that they can make using the same technology. For instance, there's a company called Clara Foods, and they are focusing on egg white proteins. They foresee using it - some of it to boost the protein content in, say, sports drinks. There is a company called Motif Ingredients that's actually looking at a whole host of proteins derived from animals, including egg and dairy and meat. And they want to become a ingredient supplier, including to all the plant-based food companies that are popping up.

SHAPIRO: So the McDonald's, the Shake Shacks, the Burger Kings, the In-N-Out Burgers of the world could be making stuff that, effectively, is meat or dairy but just never actually came from an animal.

GODOY: Exactly. That's the idea.

SHAPIRO: Why is this happening now? Why are all these companies springing up at this moment?

GODOY: Well, there's a couple of reasons. One - they're seeing the success of the Impossible Burger, which uses biotechnology to create plant-based burgers that taste like real meat. And they're trying to get in on that. But the other issue is that climate change has become a more pressing issue, so a lot of consumers are looking for ways to eat less meat and animal-derived products in their diets.

SHAPIRO: What do regulators like the FDA have to say about this?

GODOY: OK, so the interesting part of this is this technology is already out there, as high-tech as it sounds. If you eat cheese, you have eaten the products of this technology. There is an enzyme called rennet that's important in cheese making, and we used to get it from the stomachs of slaughtered calves. But several decades ago, scientists figured out how to get microbes to produce the enzyme, and now a lot of the cheese we make is made using rennet from microbes.

SHAPIRO: Are there groups that oppose this?

GODOY: Yeah. Well, as you can imagine, for one thing, big dairy isn't too happy about it. And one of the things they're concerned about is that consumers will assume that products made with these proteins have all the same nutrition profile as something made with dairy from a cow. And they say, for instance, it may not have all the vitamins and minerals that that would have if it came from a cow. There's also concerns from some environmental groups. And their concern - well, one of them is that regulators won't scrutinize the technology enough. They also don't want our food supply to become even more dependent on biotech. They say technology can have repercussions you don't foresee.

SHAPIRO: NPR's Maria Godoy, thanks for the reporting and for the ice cream.

GODOY: Oh, my pleasure. Transcript provided by NPR, Copyright NPR.