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Secretary of State John Kerry sets off for what he calls "a long overdue" trip to Russia on Monday, and Syria is likely to top the agenda. But U.S.-Russian relations are frosty these days. The U.S. is imposing targeted sanctions on Russian human rights violators, while Moscow is preventing American families from adopting Russian children.

Defense attorney Judy Clarke routinely faces an enraged public, top-notch prosecutors and difficult, often disturbed clients. Now, she is soon to face those things again with another high-profile client, alleged Boston Marathon bomber Dzhokhar Tsarnaev.

Jimmie Johnson has won the Daytona 500, one day after crash during a race there injured fans. Danica Patrick, who was hoping to make history by winning, finished eighth. However, she managed to become the first woman in history to lead laps at the NASCAR race.

Steve Inskeep talks with Boston Globe columnist Juliette Kayyem about city officials' decision to lock down Boston on Friday as law enforcement searched for a suspect in the Boston Marathon bombing. Kayyem is a former top homeland security official.

Apple, Inc. is no longer the most valuable publicly traded company in the world. This week, Exxon took that spot at the top of the NASDAQ, after Apple reported profits that were lower than expected. Host Scott Simon speaks with New York Times op-ed columnist Joe Nocera about the latest Apple news, and the company's rivalry with Samsung, which seems increasingly on the upswing.

Some two dozen Americans have given $1 million or more to superPACs in the 2012 presidential campaign. The vast majority of them have been Republicans, but Jeffrey Katzenberg, the head of DreamWorks Animation, has chipped in $2 million to help out the superPAC supporting President Obama.

Mitt Romney flies to Israel this weekend on the second leg of his overseas tour. He'll meet with top Israeli officials as well as the Palestinian prime minister. The Republican presidential candidate is using the trip to court the Jewish vote, which went overwhelmingly for Barack Obama in 2008.

The opposition in Syria delivered a powerful blow to President Bashar Assad's regime Wednesday. A bomb attack killed the country's top security officials. Renee Montagne talks to Liz Sly of The Washington Post about the ongoing clashes.

A meal in a Tripoli restaurant prompts questions about how to cook camel and its history as a food.

President Trump and Joe Biden are set to meet Thursday for their second and final debate. With 12 days until the election, it's perhaps the last opportunity for the campaigns to change course.